Transcription factor C/EBPβ isoform ratio regulates osteoclastogenesis through MafB

Disequilibrium between bone-forming osteoblasts and bone-resorbing osteoclasts is central to many bone diseases. Here, we show that dysregulated expression of translationally controlled isoforms of CCAAT/enhancer-binding protein β (C/EBPβ) differentially affect bone mass. Alternative translation ini...

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Autors principals: Smink, Jeske J, Bégay, Valérie, Schoenmaker, Ton, Sterneck, Esta, de Vries, Teun J, Leutz, Achim
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685610/
https://ncbi.nlm.nih.gov/pubmed/19440205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.127
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