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Loss of genetic accuracy in mutants of the thermoacidophile Sulfolobus acidocaldarius

To investigate how hyperthermophilic archaea can propagate their genomes accurately, we isolated Sulfolobus acidocaldarius mutants exhibiting abnormally high rates of spontaneous mutation. Our isolation strategy involved enrichment for mutator lineages via alternating selections, followed by screeni...

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Bibliografische gegevens
Hoofdauteurs: Bell, Greg D., Grogan, Dennis W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Heron Publishing 2002
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685545/
https://ncbi.nlm.nih.gov/pubmed/15803658
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