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Loss of genetic accuracy in mutants of the thermoacidophile Sulfolobus acidocaldarius

To investigate how hyperthermophilic archaea can propagate their genomes accurately, we isolated Sulfolobus acidocaldarius mutants exhibiting abnormally high rates of spontaneous mutation. Our isolation strategy involved enrichment for mutator lineages via alternating selections, followed by screeni...

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Sonraí Bibleagrafaíochta
Main Authors: Bell, Greg D., Grogan, Dennis W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Heron Publishing 2002
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685545/
https://ncbi.nlm.nih.gov/pubmed/15803658
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