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Post-transcriptional control of DGCR8 expression by the Microprocessor

The Microprocessor, comprising the RNase III Drosha and the double-stranded RNA binding protein DGCR8, is essential for microRNA (miRNA) biogenesis. In the miRNA processing pathway certain hairpin structures within primary miRNA (pri-miRNA) transcripts are specifically cleaved by the Microprocessor...

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Détails bibliographiques
Auteurs principaux: Triboulet, Robinson, Chang, Hao-Ming, LaPierre, Robert J., Gregory, Richard I.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685516/
https://ncbi.nlm.nih.gov/pubmed/19383765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1591709
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