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FINDSITE(LHM): A Threading-Based Approach to Ligand Homology Modeling

Ligand virtual screening is a widely used tool to assist in new pharmaceutical discovery. In practice, virtual screening approaches have a number of limitations, and the development of new methodologies is required. Previously, we showed that remotely related proteins identified by threading often s...

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Autors principals: Brylinski, Michal, Skolnick, Jeffrey
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685473/
https://ncbi.nlm.nih.gov/pubmed/19503616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000405
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