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Inflammatory Cytokine Tumor Necrosis Factor α Confers Precancerous Phenotype in an Organoid Model of Normal Human Ovarian Surface Epithelial Cells

In this study, we established an in vitro organoid model of normal human ovarian surface epithelial (HOSE) cells. The spheroids of these normal HOSE cells resembled epithelial inclusion cysts in human ovarian cortex, which are the cells of origin of ovarian epithelial tumor. Because there are strong...

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Detalhes bibliográficos
Main Authors: Kwong, Joseph, Chan, Franky Leung, Wong, Kwong-kwok, Birrer, Michael J, Archibald, Kyra M, Balkwill, Frances R, Berkowitz, Ross S, Mok, Samuel C
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685442/
https://ncbi.nlm.nih.gov/pubmed/19484142
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