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Stretch-activated channel activation promotes early afterdepolarizations in rat ventricular myocytes under oxidative stress
Mechanical stretch and oxidative stress have been shown to prolong action potential duration (APD) and produce early afterdepolarizations (EADs). Here, we developed a simulation model to study the role of stretch-activated channel (SAC) currents in triggering EADs in ventricular myocytes under oxida...
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| Huvudupphovsmän: | , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Physiological Society
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2685334/ https://ncbi.nlm.nih.gov/pubmed/19286952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00808.2008 |
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