Identification of the B-Raf/Mek/Erk MAP kinase pathway as a target for all-trans retinoic acid during skin cancer promotion

BACKGROUND: Retinoids have been studied extensively for their potential as therapeutic and chemopreventive agents for a variety of cancers, including nonmelanoma skin cancer (NMSC). Despite their use for many years, the mechanism of action of retinoids in the prevention of NMSC is still unclear. In...

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Detalhes bibliográficos
Main Authors: Cheepala, Satish B, Yin, Weihong, Syed, Zanobia, Gill, Jennifer N, McMillian, Alaina, Kleiner, Heather E, Lynch, Mark, Loganantharaj, Rasiah, Trutschl, Marjan, Cvek, Urska, Clifford, John L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685120/
https://ncbi.nlm.nih.gov/pubmed/19432991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-27
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