Structural basis of tRNA modification with CO(2) fixation and methylation by wybutosine synthesizing enzyme TYW4

Wybutosine (yW), one of the most complicated modified nucleosides, is found in the anticodon loop of eukaryotic phenylalanine tRNA. This hypermodified nucleoside ensures correct codon recognition by stabilizing codon-anticodon pairings during the decoding process in the ribosome. TYW4 is an S-adenos...

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Bibliographic Details
Main Authors: Suzuki, Yoko, Noma, Akiko, Suzuki, Tsutomu, Ishitani, Ryuichiro, Nureki, Osamu
Format: Artigo
Language:Inglês
Published: Oxford University Press 2009
Subjects:
Structural Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685095/
https://ncbi.nlm.nih.gov/pubmed/19287006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp158
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