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Copper Regulation of Hypoxia-Inducible Factor-1 Activity

Previous studies have demonstrated that copper up-regulates hypoxia-inducible factor 1 (HIF-1). The present study was undertaken to test the hypothesis that copper is required for HIF-1 activation. Treatment of HepG2 cells with a copper chelator tetraethylenepentamine (TEPA) or short interfering RNA...

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Bibliografiset tiedot
Päätekijät: Feng, Wenke, Ye, Fei, Xue, Wanli, Zhou, Zhanxiang, Kang, Y. James
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Pharmacology and Experimental Therapeutics 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685058/
https://ncbi.nlm.nih.gov/pubmed/18842833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.051516
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