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Metallothionein Rescues Hypoxia-Inducible Factor-1α Transcriptional Activity in Cardiomyocytes under Diabetic Conditions
Metallothionein (MT) is effective in the prevention of diabetic cardiomyopathy, and hypoxia-inducible factor 1α (HIF-1α) is known to control VEGF gene expression and regulate angiogenesis in diabetic hearts. We examined whether or not MT affects HIF-1α activity in the heart of diabetic mice and in t...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458699/ https://ncbi.nlm.nih.gov/pubmed/17586470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.06.057 |
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