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Desipramine Reduces Stress-Activated Dynorphin Expression and CREB Phosphorylation in NAc Tissue

The nucleus accumbens (NAc) is a critical brain area for reward and motivated behavior. Accumulating evidence suggests that altered function of the transcription factor cAMP response element binding protein (CREB) within the NAc is involved in depressive behavior. In rats, stress activates CREB with...

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Detalhes bibliográficos
Main Authors: Chartoff, Elena H., Papadopoulou, Maria, MacDonald, Matt L., Parsegian, Aram, Potter, David, Konradi, Christine, Carlezon, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684917/
https://ncbi.nlm.nih.gov/pubmed/19106229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.051417
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