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Targeting Protein Serine/Threonine Phosphatases for Drug Development
With the recent clinical success of drugs targeting protein kinase activity, drug discovery efforts are focusing on the role of reversible protein phosphorylation in disease states. The activity of protein phosphatases, enzymes that oppose protein kinases, can also be manipulated to alter cellular s...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Pharmacology and Experimental Therapeutics
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2684880/ https://ncbi.nlm.nih.gov/pubmed/19299564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.053140 |
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