Comparative study of the persistence of anti-HIV activity of deoxynucleoside HIV reverse transcriptase inhibitors after removal from culture

BACKGROUND: Most in vitro assays of drug potency may not adequately predict the performance in vivo. Methods to assess the persistence of antiviral activity of deoxynucleoside analogs, which require intracellular activation to the active metabolites that can persist in cells, will be important for d...

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Main Authors: Paintsil, Elijah, Grill, Susan P, Dutschman, Ginger E, Cheng, Yung-Chi
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684870/
https://ncbi.nlm.nih.gov/pubmed/19386130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-6405-6-5
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