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Characterizing Metabolic Inhibition Using Electrochemical Enzyme-DNA Biosensors

Studies of metabolic enzyme inhibition are necessary in drug development and toxicity investigations as potential tools to limit or prevent appearance of deleterious metabolites formed, for example by cytochrome (cyt) P450 enzymes. In this paper, we evaluate the use of enzyme/DNA toxicity biosensors...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hull, Dominic O., Bajrami, Besnik, Jansson, Ingela, Schenkman, John B., Rusling, James F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684828/
https://ncbi.nlm.nih.gov/pubmed/19099359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac802179s
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