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Suppression of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Nitric-Oxide Synthase 2 Expression in Astrocytes by a Novel Diindolylmethane Analog Protects Striatal Neurons against Apoptosis

The progressive debilitation of motor functions in Parkinson's disease (PD) results from degeneration of dopaminergic neurons within the substantia nigra pars compacta of the midbrain. Long-term inflammatory activation of microglia and astrocytes plays a central role in the progression of PD an...

詳細記述

保存先:
書誌詳細
主要な著者: Carbone, David. L., Popichak, Katriana A., Moreno, Julie A., Safe, Stephen, Tjalkens, Ronald B.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Pharmacology and Experimental Therapeutics 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684683/
https://ncbi.nlm.nih.gov/pubmed/18840677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.050781
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