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Quantifying DNA Melting Transitions Using Single-Molecule Force Spectroscopy
We stretched a DNA molecule using atomic force microscope and quantified the mechanical properties associated with B and S forms of double-stranded DNA (dsDNA), molten DNA, and single-stranded DNA (ssDNA). We also fit overdamped diffusion models to the AFM time series and used these models to extrac...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2684650/ https://ncbi.nlm.nih.gov/pubmed/20046972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/0953-8984/21/3/034114 |
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