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Experimental Free Energy Surface Reconstruction From Single-Molecule Force Spectroscopy Using Jarzynski’s Equality

We used the atomic force microscope to manipulate and unfold individual molecules of the titin I27 domain and reconstructed its free energy surface using Jarzynski’s equality. The free energy surface for both stretching and unfolding was reconstructed using an exact formula that relates the nonequil...

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Библиографические подробности
Главные авторы: Harris, Nolan C., Song, Yang, Kiang, Ching-Hwa
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682736/
https://ncbi.nlm.nih.gov/pubmed/17930869
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