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Experimental Free Energy Surface Reconstruction From Single-Molecule Force Spectroscopy Using Jarzynski’s Equality

We used the atomic force microscope to manipulate and unfold individual molecules of the titin I27 domain and reconstructed its free energy surface using Jarzynski’s equality. The free energy surface for both stretching and unfolding was reconstructed using an exact formula that relates the nonequil...

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Bibliographic Details
Main Authors: Harris, Nolan C., Song, Yang, Kiang, Ching-Hwa
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682736/
https://ncbi.nlm.nih.gov/pubmed/17930869
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