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Enhanced cytotoxicity of TATp-bearing paclitaxel-loaded micelles in vitro and in vivo

Cell-penetrating peptide (TATp) was attached to the distal tips of polyethylene glycol (PEG) moieties of polyethyleneglycol-phosphatidylethanolamine (PEG-PE) micelles loaded with paclitaxel (PCT). The TATp-modified micelles demonstrated an increased interaction with cancer cells compared to non-modi...

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Détails bibliographiques
Auteurs principaux: Sawant, Rupa R., Torchilin, Vladimir P.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684523/
https://ncbi.nlm.nih.gov/pubmed/19446767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2009.02.022
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