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Hydrotropic Polymeric Micelles for Enhanced Paclitaxel Solubility: In Vitro and In Vivo Characterization

The purpose of this investigation was to characterize the in vitro stability and in vivo disposition of paclitaxel in rats after solubilization of paclitaxel into hydrotropic polymeric micelles. The amphiphilic block copolymers consisted of micellar a shell-forming poly(ethylene glycol) (PEG) block...

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Detalhes bibliográficos
Main Authors: Lee, Sang Cheon, Huh, Kang Moo, Lee, Jaehwi, Cho, Yong Woo, Galinsky, Raymond E., Park, Kinam
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532792/
https://ncbi.nlm.nih.gov/pubmed/17206808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm060307b
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