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Hydrotropic Polymeric Micelles for Enhanced Paclitaxel Solubility: In Vitro and In Vivo Characterization

The purpose of this investigation was to characterize the in vitro stability and in vivo disposition of paclitaxel in rats after solubilization of paclitaxel into hydrotropic polymeric micelles. The amphiphilic block copolymers consisted of micellar a shell-forming poly(ethylene glycol) (PEG) block...

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Autori principali: Lee, Sang Cheon, Huh, Kang Moo, Lee, Jaehwi, Cho, Yong Woo, Galinsky, Raymond E., Park, Kinam
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532792/
https://ncbi.nlm.nih.gov/pubmed/17206808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm060307b
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