Inducible Nitric Oxide Synthase Deficiency Impairs Matrix Metalloproteinase-9 Activity and Disrupts Leukocyte Migration in Hepatic Ischemia/Reperfusion Injury

Matrix metalloproteinase 9 (MMP-9) is a critical mediator of leukocyte migration in hepatic ischemia/reperfusion (I/R) injury. To test the relevance of inducible nitric oxide synthase (iNOS) expression on the regulation of MMP-9 activity in liver I/R injury, our experiments included both iNOS-defici...

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Main Authors: Hamada, Takashi, Duarte, Sergio, Tsuchihashi, Seiichiro, Busuttil, Ronald W., Coito, Ana J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2009
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684191/
https://ncbi.nlm.nih.gov/pubmed/19443702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080872
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