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Rats selectively bred for low aerobic capacity have reduced hepatic mitochondrial oxidative capacity and susceptibility to hepatic steatosis and injury

Fatty liver has been linked to low aerobic fitness, but the mechanisms are unknown. We previously reported a novel model in which rats were artificially selected to be high capacity runners (HCR) and low capacity runners (LCR) that in a sedentary condition have robustly different intrinsic aerobic c...

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Bibliografiske detaljer
Main Authors: Thyfault, John P, Rector, R Scott, Uptergrove, Grace M, Borengasser, Sarah J, Morris, E Matthew, Wei, Yongzhong, Laye, Matt J, Burant, Charles F, Qi, Nathan R, Ridenhour, Suzanne E, Koch, Lauren G, Britton, Steve L, Ibdah, Jamal A
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683966/
https://ncbi.nlm.nih.gov/pubmed/19237421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.169060
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