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Rats selectively bred for low aerobic capacity have reduced hepatic mitochondrial oxidative capacity and susceptibility to hepatic steatosis and injury

Fatty liver has been linked to low aerobic fitness, but the mechanisms are unknown. We previously reported a novel model in which rats were artificially selected to be high capacity runners (HCR) and low capacity runners (LCR) that in a sedentary condition have robustly different intrinsic aerobic c...

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Detalhes bibliográficos
Main Authors: Thyfault, John P, Rector, R Scott, Uptergrove, Grace M, Borengasser, Sarah J, Morris, E Matthew, Wei, Yongzhong, Laye, Matt J, Burant, Charles F, Qi, Nathan R, Ridenhour, Suzanne E, Koch, Lauren G, Britton, Steve L, Ibdah, Jamal A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683966/
https://ncbi.nlm.nih.gov/pubmed/19237421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.169060
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