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The nsP3 macro domain is important for Sindbis virus replication in neurons and neurovirulence in mice
Sindbis virus (SINV), the prototype alphavirus, contains a macro domain in the highly conserved N-terminal region of nonstructural protein 3 (nsP3). However, the biological role of the macro domain is unclear. Mutations of amino acids 10 and 24 from asparagine to alanine in the ADP-ribose binding re...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier Inc.
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2683903/ https://ncbi.nlm.nih.gov/pubmed/19395054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.03.031 |
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