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Kaposi's Sarcoma-Associated Herpesvirus-G Protein-Coupled Receptor-Expressing Endothelial Cells Exhibit Reduced Migration and Stimulated Chemotaxis by Chemokine Inverse Agonists

A constitutively active G protein-coupled receptor (GPCR) encoded by Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8) (KSHV) is expressed in endothelial (spindle) cells of Kaposi's sarcoma lesions. In this study, we report novel effects of basal signaling by this receptor and...

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Hlavní autoři: Couty, Jean-Pierre, Lupu-Meiri, Monica, Oron, Yoram, Gershengorn, Marvin C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Pharmacology and Experimental Therapeutics 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683784/
https://ncbi.nlm.nih.gov/pubmed/19258523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.147686
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