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CTLA4 expression is an indicator and regulator of steady-state CD4(+)FoxP3(+) T cell homeostasis
The presence of FoxP3(+) regulatory T cells (Tregs) is necessary for control of deleterious immune responses in the steady-state; however, mechanisms for maintaining the frequency and quality of endogenous Tregs are not well-defined. In this study, we used in vivo modulators of the CD28 and CTLA4 pa...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2683757/ https://ncbi.nlm.nih.gov/pubmed/18641318 |
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