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Proximal signaling control of human effector CD4 T cell function

The functional coupling of T cell receptor (TCR)-mediated signaling events in primary human T cells remains undefined. We demonstrate here that alterations in the expression of proximal TCR-coupled signaling subunits are associated with distinct effector capacities in differentiated human CD4 T cell...

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Main Authors: Okoye, Francesca I., Krishnan, Sandeep, Chandok, Meena R., Tsokos, George C., Farber, Donna L.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683756/
https://ncbi.nlm.nih.gov/pubmed/17692570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2007.07.002
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