Profilin 1 is required for abscission during late cytokinesis of chondrocytes

Profilins are key factors for dynamic rearrangements of the actin cytoskeleton. However, the functions of profilins in differentiated mammalian cells are uncertain because profilin deficiency is early embryonic lethal for higher eukaryotes. To examine profilin function in chondrocytes, we disrupted...

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Bibliographic Details
Main Authors: Böttcher, Ralph T, Wiesner, Sebastian, Braun, Attila, Wimmer, Reiner, Berna, Alejandro, Elad, Nadav, Medalia, Ohad, Pfeifer, Alexander, Aszódi, Attila, Costell, Mercedes, Fässler, Reinhard
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683706/
https://ncbi.nlm.nih.gov/pubmed/19262563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.58
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