Profilin 1 is required for abscission during late cytokinesis of chondrocytes

Profilins are key factors for dynamic rearrangements of the actin cytoskeleton. However, the functions of profilins in differentiated mammalian cells are uncertain because profilin deficiency is early embryonic lethal for higher eukaryotes. To examine profilin function in chondrocytes, we disrupted...

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Main Authors: Böttcher, Ralph T, Wiesner, Sebastian, Braun, Attila, Wimmer, Reiner, Berna, Alejandro, Elad, Nadav, Medalia, Ohad, Pfeifer, Alexander, Aszódi, Attila, Costell, Mercedes, Fässler, Reinhard
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683706/
https://ncbi.nlm.nih.gov/pubmed/19262563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.58
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