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Rad52 recruitment is DNA replication independent and regulated by Cdc28 and the Mec1 kinase

Recruitment of the homologous recombination machinery to sites of double-strand breaks is a cell cycle-regulated event requiring entry into S phase and CDK1 activity. Here, we demonstrate that the central recombination protein, Rad52, forms foci independent of DNA replication, and its recruitment re...

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Detalhes bibliográficos
Main Authors: Barlow, Jacqueline H, Rothstein, Rodney
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683695/
https://ncbi.nlm.nih.gov/pubmed/19262568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.43
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