Induced Autoimmunity to Heat Shock Proteins Elicits Glaucomatous Loss of Retinal Ganglion Cell Neurons via Activated T-Cell-Derived Fas-Ligand

Glaucomatous optic neuropathy causes blindness through the degeneration of retinal ganglion cells (RGCs) and their axons, which comprise the optic nerve. Glaucoma traditionally is associated with elevated intraocular pressure, but often occurs or may progress with intraocular pressure in the normal...

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Main Authors: Wax, Martin B., Tezel, Gülgün, Yang, Junjie, Peng, Guanghua, Patil, Rajkumar V., Agarwal, Neeraj, Sappington, Rebecca M., Calkins, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683273/
https://ncbi.nlm.nih.gov/pubmed/19005073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3200-08.2008
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