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A Single Intra-PFC Infusion of BDNF Prevents Cocaine-Induced Alterations in Extracellular Glutamate within the Nucleus Accumbens

The glutamatergic pathway arising in the dorsomedial prefrontal cortex (dmPFC) and projecting to the nucleus accumbens (NAc) core is a critical component of the reward circuitry that underlies reinstatement to cocaine-seeking behavior. Brain-derived neurotrophic factor (BDNF) is expressed by and mod...

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Главные авторы: Berglind, William J., Whitfield, Timothy W., LaLumiere, Ryan T., Kalivas, Peter W., McGinty, Jacqueline F.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683065/
https://ncbi.nlm.nih.gov/pubmed/19321768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5457-08.2009
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