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The structure of Atg4B–LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy
Atg8 is conjugated to phosphatidylethanolamine (PE) by ubiquitin-like conjugation reactions. Atg8 has at least two functions in autophagy: membrane biogenesis and target recognition. Regulation of PE conjugation and deconjugation of Atg8 is crucial for these functions in which Atg4 has a critical fu...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2683054/ https://ncbi.nlm.nih.gov/pubmed/19322194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.80 |
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