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Observation of strange kinetics in protein folding

Highly nonexponential folding kinetics in aqueous solution have been observed during temperature jump-induced refolding of two proteins, yeast phosphoglycerate kinase and a ubiquitin mutant. The observations are most easily interpreted in terms of downhill folding, which posits a heterogeneous ensem...

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Detalles Bibliográficos
Main Authors: Sabelko, J., Ervin, J., Gruebele, M.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC26830/
https://ncbi.nlm.nih.gov/pubmed/10339536
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