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Minimalist proteins: Design of new molecular recognition scaffolds
We hypothesize that we can exploit what Nature has already evolved by manipulating the α-helix molecular recognition scaffold. Therefore, minimalist proteins capable of sequence-specific, high-affinity binding of DNA were generated to probe how proteins are used and can be used to recognize DNA. The...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2004
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2682982/ https://ncbi.nlm.nih.gov/pubmed/19461942 |
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