JNK-Induced MCP-1 Production in Spinal Cord Astrocytes Contributes to Central Sensitization and Neuropathic Pain

Our previous study showed that activation of c-jun-N-terminal kinase (JNK) in spinal astrocytes plays an important role in neuropathic pain sensitization. We further investigated how JNK regulates neuropathic pain. In cultured astrocytes, tumor necrosis factor α (TNF-α) transiently activated JNK via...

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Autori principali: Gao, Yong-Jing, Zhang, Ling, Samad, Omar Abdel, Suter, Marc R., Yasuhiko, Kawasaki, Xu, Zhen-Zhong, Park, Jong-Yeon, Lind, Anne-Li, Ma, Qiufu, Ji, Ru-Rong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682921/
https://ncbi.nlm.nih.gov/pubmed/19339605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3623-08.2009
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