Intracellular Transport of Human Immunodeficiency Virus Type 1 Genomic RNA and Viral Production Are Dependent on Dynein Motor Function and Late Endosome Positioning

Our earlier work indicated that the human immunodeficiency virus type 1 (HIV-1) genomic RNA (vRNA) is trafficked to the microtubule-organizing center (MTOC) when heterogeneous nuclear ribonucleoprotein A2/B1 is depleted from cells. Also, Rab7-interacting lysosomal protein promoted dynein motor compl...

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Bibliografske podrobnosti
Main Authors: Lehmann, Martin, Milev, Miroslav P., Abrahamyan, Levon, Yao, Xiao-Jian, Pante, Nelly, Mouland, Andrew J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
RNA: Processing and Catalysis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682905/
https://ncbi.nlm.nih.gov/pubmed/19286658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808531200
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