Axonal autophagosomes recruit dynein for retrograde transport through fusion with late endosomes

Efficient degradation of autophagic vacuoles (AVs) via lysosomes is an important cellular homeostatic process. This is particularly challenging for neurons because mature acidic lysosomes are relatively enriched in the soma. Although dynein-driven retrograde transport of AVs was suggested, a fundame...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Cheng, Xiu-Tang, Zhou, Bing, Lin, Mei-Yao, Cai, Qian, Sheng, Zu-Hang
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2015
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427784/
https://ncbi.nlm.nih.gov/pubmed/25940348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201412046
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