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The Carboxyl-terminal Domain of Atypical Protein Kinase Cζ Binds to Ceramide and Regulates Junction Formation in Epithelial Cells
Atypical protein kinase Cs (PKCs) (aPKCζ and λ/ι) have emerged as important binding partners for ceramide, a membrane-resident cell signaling lipid that is involved in the regulation of apoptosis as well as cell polarity. Using ceramide overlay assays with proteolytic fragments of PKCζ and vesicle b...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2682895/ https://ncbi.nlm.nih.gov/pubmed/19304661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808909200 |
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