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Wnt11 Promotes Osteoblast Maturation and Mineralization through R-spondin 2

Wnt11 signals through both canonical (β-catenin) and non-canonical pathways and is up-regulated during osteoblast differentiation and fracture healing. In these studies, we evaluated the role of Wnt11 during osteoblastogenesis. Wnt11 overexpression in MC3T3E1 pre-osteoblasts increases β-catenin accu...

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Detalhes bibliográficos
Main Authors: Friedman, Michael S., Oyserman, Sivan M., Hankenson, Kurt D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682860/
https://ncbi.nlm.nih.gov/pubmed/19213727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808337200
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