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Developing a novel rabbit model of atherosclerotic plaque rupture and thrombosis by cold-induced endothelial injury

BACKGROUND: It is widely believed that atherosclerotic plaque rupture and subsequent thrombosis leads to acute coronary events and stroke. However, study of the mechanism and treatment of human plaque rupture is hampered by lack of a suitable animal model. Our aim was to develop a novel animal model...

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Autors principals: Fang, Shun-Miao, Zhang, Qing-Hua, Jiang, Zhi-Xin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682487/
https://ncbi.nlm.nih.gov/pubmed/19344521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-16-39
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