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Developing a novel rabbit model of atherosclerotic plaque rupture and thrombosis by cold-induced endothelial injury

BACKGROUND: It is widely believed that atherosclerotic plaque rupture and subsequent thrombosis leads to acute coronary events and stroke. However, study of the mechanism and treatment of human plaque rupture is hampered by lack of a suitable animal model. Our aim was to develop a novel animal model...

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Detalhes bibliográficos
Main Authors: Fang, Shun-Miao, Zhang, Qing-Hua, Jiang, Zhi-Xin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682487/
https://ncbi.nlm.nih.gov/pubmed/19344521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-16-39
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