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Sources of Tissue Factor that contribute to Thrombosis after Rupture of an Atherosclerotic Plaque

Hyperlipidemia leads to the formation of oxidized LDL (oxLDL), vessel dysfunction, atherosclerotic disease, and ultimately to plaque rupture and thrombosis. OxLDL induces tissue factor (TF) expression in various cell types, including monocytes and macrophages. High levels of TF are present in athero...

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Detalhes bibliográficos
Publicado no:Thromb Res
Main Authors: Owens, A. Phillip, Mackman, Nigel
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885765/
https://ncbi.nlm.nih.gov/pubmed/22444158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2012.02.026
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