Phenotypic and Molecular Evaluation of a Chromosome 1q Region with Linkage and Association to Type 2 Diabetes in Humans

Objective: Linkage to type 2 diabetes (T2D) is well replicated on chromosome 1q21-q23. Within this region, T2D was associated with common single nucleotide polymorphisms that marked an extended linkage disequilibrium block, including the liver pyruvate kinase gene (PKLR), in several European-derived...

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Main Authors: Wang, Hua, Hays, Nicholas P., Das, Swapan K., Craig, Rebekah L., Chu, Winston S., Sharma, Neeraj, Elbein, Steven C.
Format: Artigo
Jezik:Inglês
Izdano: The Endocrine Society 2009
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682467/
https://ncbi.nlm.nih.gov/pubmed/19141583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2008-2132
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