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Engineered adenosine-releasing cells for epilepsy therapy: Human mesenchymal stem cells and human embryonic stem cells
Adenosine is a modulator of neuronal activity with anticonvulsant and neuroprotective properties. Conversely, focal deficiency in adenosine contributes to ictogenesis. Thus, focal reconstitution of adenosine within an epileptogenic brain region constitutes a rational therapeutic approach, whereas sy...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2682344/ https://ncbi.nlm.nih.gov/pubmed/19332320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nurt.2008.12.001 |
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