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ROLE AND REGULATION OF FERRITIN H IN ROTENONE-MEDIATED MITOCHONDRIAL OXIDATIVE STRESS

Tight regulation of intracellular iron levels in response to mitochondrial dysfunction is an important mechanism that prevents oxidative stress, thereby limiting cellular damage. Here, we describe a cytoprotective response involving transcriptional activation of the ferritin H gene in response to th...

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Detalhes bibliográficos
Main Authors: MacKenzie, Elizabeth L., Ray, Paul D., Tsuji, Yoshiaki
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682214/
https://ncbi.nlm.nih.gov/pubmed/18325346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.01.031
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