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HPMA Polymer-based Site-specific Delivery of Oligonucleotides to Hepatic Stellate Cells

The objective was to determine whether bioconjugation of type I collagen specific triplex forming oligonucleotide (TFO) to N-(2-hydroxypropyl) methacrylamide (HPMA) containing tetrapeptide Gly-Phe-Leu-Gly (GFLG) and mannose 6-phosphate (M6P) can provide their targeted delivery to hepatic stellate ce...

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Detalhes bibliográficos
Main Authors: Yang, Ningning, Ye, Zhaoyang, Li, Feng, Mahato, Ram I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682209/
https://ncbi.nlm.nih.gov/pubmed/19133717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc800237t
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