Impact of Human Immunodeficiency Virus Type 1 Resistance to Protease Inhibitors on Evolution of Resistance to the Maturation Inhibitor Bevirimat (PA-457)

The maturation inhibitor bevirimat [3-O-(3′,3′dimethysuccinyl)betulinic acid; BVM; also known as PA-457 or DSB] potently inhibits human immunodeficiency virus type 1 (HIV-1) replication by blocking protease (PR)-mediated cleavage at the junction between capsid (CA) and spacer peptide 1 (SP1) in Gag....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Adamson, Catherine S., Waki, Kayoko, Ablan, Sherimay D., Salzwedel, Karl, Freed, Eric O.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2009
Gaiak:
Vaccines and Antiviral Agents
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682084/
https://ncbi.nlm.nih.gov/pubmed/19279107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02659-08
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