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Pak4, a Novel Gab1 Binding Partner, Modulates Cell Migration and Invasion by the Met Receptor

Hepatocyte growth factor (HGF), the ligand for the Met receptor tyrosine kinase, induces epithelial cell dispersal, invasion, and morphogenesis, events that require remodeling of the actin cytoskeleton. The scaffold protein Gab1 is essential for these biological responses downstream from Met. We hav...

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Détails bibliographiques
Auteurs principaux: Paliouras, Grigorios N., Naujokas, Monica A., Park, Morag
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682017/
https://ncbi.nlm.nih.gov/pubmed/19289496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01286-08
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