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Pak4, a Novel Gab1 Binding Partner, Modulates Cell Migration and Invasion by the Met Receptor

Hepatocyte growth factor (HGF), the ligand for the Met receptor tyrosine kinase, induces epithelial cell dispersal, invasion, and morphogenesis, events that require remodeling of the actin cytoskeleton. The scaffold protein Gab1 is essential for these biological responses downstream from Met. We hav...

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Detalhes bibliográficos
Main Authors: Paliouras, Grigorios N., Naujokas, Monica A., Park, Morag
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682017/
https://ncbi.nlm.nih.gov/pubmed/19289496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01286-08
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