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Pak4, a Novel Gab1 Binding Partner, Modulates Cell Migration and Invasion by the Met Receptor
Hepatocyte growth factor (HGF), the ligand for the Met receptor tyrosine kinase, induces epithelial cell dispersal, invasion, and morphogenesis, events that require remodeling of the actin cytoskeleton. The scaffold protein Gab1 is essential for these biological responses downstream from Met. We hav...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology (ASM)
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2682017/ https://ncbi.nlm.nih.gov/pubmed/19289496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01286-08 |
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