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Pak4, a Novel Gab1 Binding Partner, Modulates Cell Migration and Invasion by the Met Receptor

Hepatocyte growth factor (HGF), the ligand for the Met receptor tyrosine kinase, induces epithelial cell dispersal, invasion, and morphogenesis, events that require remodeling of the actin cytoskeleton. The scaffold protein Gab1 is essential for these biological responses downstream from Met. We hav...

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Detalles Bibliográficos
Autores principales: Paliouras, Grigorios N., Naujokas, Monica A., Park, Morag
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682017/
https://ncbi.nlm.nih.gov/pubmed/19289496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01286-08
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